Passive SOBP generation from a static proton pencil beam using 3D-printed range modulators for FLASH experiments

نویسندگان

چکیده

The University Proton Therapy facility in Dresden (UPTD), Germany, is equipped with an experimental room a beamline providing static pencil beam. High proton beam currents can be achieved at this which makes it suitable for FLASH experiments. However, the established setup uses only entrance channel of Bragg curve. In work, set 3D-printed range modulators designed to generate spread out peaks (SOBPs) radiobiological experiments ultra-high dose rate described. A new method optimize specifically case based on central depth profile introduced. Modulators two different irradiation setups were produced and characterized experimentally by measurements lateral distributions using detectors. addition, Monte Carlo simulations performed assess profiles averaged linear energy transfer ( LET D ) water. These newly will allow future SOBP UPTD setups.

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ژورنال

عنوان ژورنال: Frontiers in Physics

سال: 2023

ISSN: ['2296-424X']

DOI: https://doi.org/10.3389/fphy.2023.1213779